Most Evil Popes in the History of Mankind

Have safe sex with Condoms Cause Gonorrhoea Would soon become Untreatable - CDC cautions

Rising Untreatable "Super bug" Gonorrhoea Spreading Globally

     Gonorrhoea known commonly as “the clap” or “the drip” is the second most common bacteria sexually transmitted infection (STI) in the UK after Chlamydia, with almost 35,000 cases reported in England in 2014, And about 78 million people catch gonorrhoea every year. Anyone who is sexually active is at risk and any kind of sex, including anal and oral sex, can pass it along.

It was once easily treated with a quick dose of antibiotics but, like all bacterial infections, strains have evolved that can evade the mechanisms used by antibiotics “Gonorrhoea is a very smart bud” said Teodora Wi, a human reproduction specialist at the Geneva-based UN health agency. “Every time you introduce a new type of antibiotic to treat it, this bug develops resistance to it.”

   But the new antibiotic resistant strain developed through a mistreatment of gonorrhoea bacteria left in the throat after oral sex. Gonorrhoea in the throat often looks like strep throat, so doctors prescribe standard antibiotics, which then mix with the bacteria creating antibiotic-resistant gonorrhoea. Both of the current antibiotics used to treat gonorrhoea- Ceftriaxone and Azithromycin are becoming increasingly ineffective against the new strain.

“To date, three extensively drug resistant gonococcal strains with high-level resistance to ceftriaxone (super-bugs) have also been reported- in France, Japan and Spain” Wi and colleagues wrote in their report.

 

U.S. authorities have had some success against gonorrhoea by using both Ceftriaxone and azithromycin- but it’s unclear how long such a regimen will deter the super gonorrhoea.

The WHO reports urges countries to encourage the development of new drugs and a vaccine against gonorrhoea and urges better surveillance and treatment in the meantime.

     Three new drugs are in the development pipeline, solithromycin, which has completed a phase III Trial, and two other drugs which have completed phase II trials, but it is unclear how long it will take these drugs to reach the pharmaceutical market and whether they will prove to be stronger than the super-bug

Before Then, health experts recommend safe sex with condoms, communication with partners, frequent testing, and old boring standby, abstinence.

   According to the CDC, symptoms in men include:

• A burning sensation when urinating
• A white, Yellow or green discharge from the penis
• Painful or swollen testicles

Most women with gonorrhoea do not have any symptoms. But they can include:

• Painful or burning sensation when urinating
• Increased Vaginal discharge
• Vaginal bleeding between periods

“You can get gonorrhoea by having vaginal, anal or oral sex with someone who has gonorrhoea. A pregnant woman with gonorrhoea can give the infection to her baby during childbirth.” CDC cautions

Need to Know about Lactose Intolerance in Children

Three days ago I was invited to provide a health orientation at an Elementary school about the kind of foods which should be given to children and knowing the food they can tolerate but surprisingly people aren't aware of Food intolerance especially in this part of the world. which is getting quite common in today’s children and it can be difficult to know whether your infant or child is having symptoms of lactose intolerance or whether he or she may have a milk allergy.

For many Kids, an ice cream Sunday or cool glass of milk at lunch means an afternoon of cramps, gas and diarrhea.

What is Lactose?

Lactose is a sugar found in foods that many children love-milk and dairy products, such as frozen yoghurt, some breads, cereals and frozen canned foods. Lactose is broken down by the lactase enzyme located in small intestine. When we eat lactose, lactase breaks lactose down into two simple sugars: glucose and Galactose. The body absorbs these simple sugars into our intestine. When there is a decrease or loss of the lactase enzyme, we cannot break down or absorb lactose. The unabsorbed lactose can lead to symptoms which is called intolerance.

What is Lactose Intolerance?

Lactose intolerance is a condition caused by lack of an enzyme called lactase. Inadequate amounts of lactase cause the body to be unable to digest lactose, a sugar found in milk and milk products. The disorder affects some populations more than others: African-American, Jewish, Mexican Americans e.t.c. it is least common among people with a northern European Heritage.

What Causes Lactose Intolerance?

Injuries or Diseases at the small intestine which can reduce the amount of enzymes produced which is the usual cause of intolerance in children. But, most causes of Lactose intolerance develop over a period of many years in adolescents and adults.

Symptoms of Lactose Intolerance in Children?

Symptoms that are observed depend on the amount of Lactose that’s consumed, the time (30 minutes and 2 hours) of consumption of a diary product. Here are symptoms you should look out for:

• ·         Cramps
• ·         Painful gas
• ·         Bloating
• ·         Gas
• ·         Diarrhoea
• ·         Malnourishment
• ·         Gradual growth
• ·         Watery eyes
• ·         Coughing
• ·         Vomiting
• ·         Stools

How is Lactose Intolerance Diagnosed?

The most common diagnostic tests are used to measure the absorption in the Digestive system include:

Lactose Tolerance Test- 

This test measures the absorption of Lactose in digestive system. After Fasting, the patient drinks a Liquid that contains lactose. The diarrhoea stools are then tested for the next 24 hours.

Undigested lactose fermented by bacteria in the colon creates lactic acid and other fatty acids, which can be detected in a stool sample, along with glucose as a result of unabsorbed lactose.

Hydrogen breath Test- 

The patient drinks a lactose- heavy beverage. The breath is then analysed at regular intervals to measure the amount of hydrogen. Undigested Lactose in the colon is fermented by bacteria, resulting in the production of various gases, including hydrogen. When high levels of hydrogen are present in the breath improper digestion of lactose is diagnosed.

Stool Acidity test- 

This test used in infants and young children measures the amount of acid in the stool. Lactic acid and glucose, produced by undigested lactose,  and other fatty acids can be detected in a stool sample.

How is Lactose intolerance treated?

Treatment of Lactose intolerance depends on the extent of your child’s symptoms. Some children with lactose intolerance may be able to small amounts of dairy products without having symptoms.

·         

        Your paediatrician may recommend an over-the-counter Lactase enzyme supplement to alleviate the symptoms.

·         

        If the symptoms are severe, your paediatrician may refer your child to registered dietitian. Since dairy is a good source of calcium and vitamin D..  which all kids need while a dietitian can suggest other foods to provide those nutrients.

Finding levels of Lactose intolerance

The committee of Nutrition for the American Academy of Paediatrics recommends slowly introducing the dairy products to Judge the Child’s level of tolerance.

• ·         Some children are able to tolerate one glass of milk, but get symptoms with a second one
• ·         Some can’t tolerate milk but can tolerate yoghurt while some can tolerate hard cheese.
• ·         Keep a record of your child’s tolerance by first eliminating and slowly reintroducing specific dairy products and observing the change in symptoms.
• ·         Based on this record, you can monitor his diary intake and make sure he does not miss out on his nutrients.

Scorpion Venom used in The Treatment of Cancer Cells

           In the development of new drugs taking something from nature and modifying it has been successful tactic employed by medicinal chemists for years. Now with the use of venom, researchers are turning once- discarded drug candidates into usable drugs.

            Venom is a form of toxin secreted by some animals (e.g. scorpion, bee, snake e.tc) for the purpose of defending or causing harm to another. Off course we all know that venom can harm and kill human. However in low doses, venom will not affect normal cells while it may affect cancer cells, since cancer cells are most sensitive to e.g. modulation of various channels much needed for the very fast cellular division. Once such substance with anti-cancer potential is the cardiac glycoside Bufalin extracted from toad skin which is inhibiting a relevant ion channel for cancer cells i.e. the sodium- potassium exchange channel.

       Scorpion venom has been gaining interest as a source of new drugs, it contains a mixture of biological chemicals called peptides. Some of which are known to trigger cell death by forming proes in biological membranes.. cell death can be useful if we are able to target say tumor cells to auto-destruct.

         Investigation carried out by specialist of the Faculty of chemistry at the university of Colima (UCOL), who have identified peptides(amino acids molecules) that destroy cancer cells in vitro.

 This toxins can have very potent effects. For instance one particular small peptide known as TsAP-1, isolated from the Brazillian yellow scorpion (Tityus serrulatus) has both anti-microbial and anti cancerproperties.

            

      Laura Leticia ValdezVelazquez, Head of research, said that when the toxin, derived from scorpion venom, invades channels in the cells with this disease it produces cellular damage until killing them.

    “Centruroides tecomanus species is one of the most poisonous scorpion found in colima and we have identified a highly selective group of peptides, which indicates that they could specifically bind to cancer cells and cause their deaths” she indicates.”

        Diluted venom from blue scorpions from cuba, has been used to fight cancer for long time now by tens of thousands of patients. Though still in research phase, many patients report that tumors have disappeared upon taking the venom.

      

Mechanism of action

Kills cancer cells by ion modulation: 

A major anticancer action of scorpion venom is based on Chlorotoxin (CTX). This peptide found in the venom blocks small-conductance chloride channels that are highly relevant in some cancers for migration and invasion of healthy cells. It has been shown that chlorotoxin has the ability to interact with chloride channels in membrane protein in e.g glioma cells preventing trans-membrane chlorides fluxes .

Inhibits Metastasis:

Chlorotoxin can also bind to MMP-2 (Matrix metalloproteinase), a surface protein over-expressed in highly invasive tumours. the MMP proteins are involves in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodelling, as well as in disease processes such as arthritis and metastasis.

Although the research is at a primary stage, this indicates the use of venom from scorpions used against cancer. Experts have been observing in Labortory animals that the presence of such toxins releases dopamine, and often effective drugs have been discovered but not commerialised due to delivery of the drugs.

Reference:

Chlorotoxin: a helpful natural scorpion peptide to diagnose glioma and fight tumour invasion

http://www.ncbi.nlm.nih.gov/pubmed/25826056

Chlorotoxin is a small 36 amino- acid peptide identified from the venom of the scorpion Leiurus quinquestriatus, Initially, Chlorotoxin was used as pharmacological tool to characterize chloride channels.

Basic Ideas About Your Sleeping Position

SLEEPING POSITIONS

The moment you lie on your beds, we fix on a preferred sleeping position we aren’t most times aware of it but putting thought into it we change our “usual position”. For something so simple (even babies do easily), sleep isn’t such an easy thing. Both too little and too much dozing has been linked to a host of Health problems, From Obesity and heart disease to dementia and diabetes. And sleeping position can play a role in snoring, aches and pain, heartburn and even wrinkles! It might be time to switch things up at Bedtime.

There are 3 curves on the body that you should pay attention to

Your lower back, Middle back and near your Neck. Try to maintain these natural curves when you sleep

“Eighty Percent of the population will have back problems at some point in [their] lives often times caused or aggravated by the way they sleep,” Dr Hooman Melamed, an orthopaedic spine surgeon at the DISC Sports & Spine centre

Here is a list of sleep Position you can be aware of and there health consequence:

Side Sleeping:

This position is the most common and for some good reason, it can have a whole lot of health Benefits. If you snore or have breathing problems, sleeping on your side is the best choice for opening your airways so you can breathe better at night, says Sleep specialist W. Christopher Winter, MD Medical doctor of the Martha Jefferson Hospital Sleep Medicine Centre. Pregnant women in particular should consider sleeping in this position on their left side to ease flow of blood to the mom’s heart.

But sleeping on your side have its Disadvantages “ever slept on your side and woken up with a numb arm?” occurring as a result the weight you’re putting on your arm, or another numb body part, is putting intense pressure on your blood vessels. There can be so much crushing pressure that you lose blood circulation and you wake up to roll over, explains clinical psychologist Micheal Breus, PhD, a board-certified sleep specialist and author of GOOD NIGHT: The sleep Doctor’s 4-week Program to better sleep and Better Health. Another if you have frequent indigestion at night changing your sleep position is advisable.

Back Sleeping/The soldier:

Sleeping on your back makes your weight evenly distributed across your skeletal frame. No turning and tossing due to poor blood flow. Sleeping on your back with your knees supported upward with pillows could take some pressure off your spine and relieve pain. Sleeping with your face out in the air is a winner in reducing wrinkles. People with Heart Failure, certain respiratory Diseases, Glaucoma or Gastro-esophageal reflux Disease(GERD) may benefit from taking this position.

Stomach sleeping/freefall position:

Sleeping in this position can cause the tongue to fall inwards to block the breathing tube, they are prone to snoring and this position isn’t advisable for people with apnoea, using pillow as support isn’t preferable especially if there is neck pain.
Stomach sleeping/free fall position:

This form of sleeping if you’re a back sleeper who snores and you can ‘t switch to sleeping on your side, laying on your stomach eases breathing.

But this sleeping position isn’t advisable because it doesn’t support the natural curve of your spine, leading to your spine over arching placing pressure on the joints and muscles that leads to pain numbness and tingling.

REGARDLESS OF THE HEALTH BENEFITS!


If you sleep on your side back and stomach and you are comfortable in that position, experimenting on other positions won’t do any harm, or when you feel uncomfortable in your usual position. Unless a Doctor specifically recommends switching, it’s probably best to keep doing what feels right